Doxycycline, also known as doxycycline hydrochloride or deoxyoxytetracycline, belongs to the tetracycline antibiotics, broad-spectrum antibacterial but 2-10 times higher than oxytetracycline antibacterial activity. This is a commonly used drug for breeding, and it is used frequently. It is often used in the treatment of avian mycoplasma and porcine respiratory diseases, especially for the treatment of mixed mycoplasma and bacteria. But it is such a commonly used medicine that many farmers don't understand it and don't know how to use it! In summary, there are many kinds of bacteria, four kinds of diseases, and one kind of insects; let’s talk about it one by one:
  1. It is commonly used in these 7 situations: 1.
  Bacterial diseases, mostly used in the respiratory tract, such as pleuropneumonia and pig lung Doxycycline + florfenicol + antipyretic drugs are effective for epidemic diseases and other diseases; 2. Actinomycetes, that is, pustules that can grow in various places on pigs, in addition to Streptococcus pyogenes, there is another situation that is If it is caused by actinomycetes, doxycycline is generally more effective; 3. Common, "body" disease; mycoplasma is also asthma, and doxycycline + florfenicol (mycoplasma net) are all effective; 4. Chlamydia , the first one is abortion of sows and the pearly afterbirth should be considered, and the treatment effect is better with doxycycline; for the second kind of conjunctivitis, it is better to use tetracycline eye drops for red eyes; 5. Spirochetes (pigs) Dysentery, etc.) and Rickettsia are less used, so I won’t say more; 6. Insects are blood protozoa, which is what we often say for diseases such as epierythrocytes. Doxycycline administration is better; 7. , Oxytetracycline is generally used for prevention and treatment of sows, the damage is less and the effect is more moderate; Doxycycline is mostly used in sucking piglets after seven days, often appear yellow with white, white with gray feces ; Fat pigs often have a fever rebound during the dog days, repeatedly.
  2. How to use doxycycline to double the drug effect?
  The formula of florfenicol + doxycycline (doxycycline)
  is very common, but do you know the ratio that can double the drug effect? So what is the ratio of doxycycline? The correct ratio of doxycycline to florfenicol is 2:1, everyone must follow this ratio to dispense the medicine, otherwise the effect will not come out.
  Specific algorithm: first calculate the dosage of doxycycline, and then divide the dosage of doxycycline by 2 to get the dosage of florfenicol.
  Specific dosage: In the case of treatment, 1g of doxycycline is mixed with 6-8 catties of water, and the dosage is calculated according to this amount, otherwise, the effect will be very poor. Why increase the amount here? Here is a piece of knowledge for everyone, all tetracyclines should be used in increased doses during use.
  3. Precautions:
  1. The toxicity of this product is relatively small among the drugs in this class, and generally it will not cause flora imbalance, but it cannot be used in large doses for a long time; 2. Equine animals are sensitive to this product, and intravenous injection can cause poisoning or Death, should not be used by intravenous injection.
  3. Pay attention to doxycycline injection is more painful, pay attention to stress; 4. Why is it the first choice for the treatment of red body?
  According to foreign data, because the biological characteristics of Eperythrozoon are inconsistent with other conventional bacteria, it was initially classified as a member of the Microsporidia family (1974). Later classified as Rickettsia. However, because it is not an obligate intracellular parasite, is small, has no cell wall, is highly resistant, and is sensitive to tetracyclines. Later, after sequencing, it was found that the gene sequence similarity between the pathogen and Rickettsia was very low, but it was closer to the sequence of Mycoplasma. In recent years, the name Mycoplasma suis has been widely used in western countries, because doxycycline has a better effect on rickettsia and mycoplasma disease, and it may be that tetracyclines are more effective in treating Eperythrozoonosis porcine. In the process of treating eperythrozoonosis with tetracyclines, we found that the application of doxycycline among tetracyclines has the best effect.

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